Cholera swept a deadly path through Europe in 1832. Irish physician, William O’Shaughnessy, proposed treating patients with saline infusions and Dr Thomas Latta of Leith, successfully applied the treatment. The intravenous route is the fastest way to deliver fluids and medications through the body. Today, fluid therapy is one of the most widespread interventions in acute medicine. Clear plastic strip adhered to white paper backing, forming a sealed packet containing a cardboard backing board, with a cannula attached.Stamped in black ink on 3929.1: CAT: / NO. 1966 / CATHETER: 14 GA. / .058 I.D. / 5 1/2 IN. / 0182037 Stamped in black ink on 3929.2: CAT: / NO. 1967 / CATHETER: 16 GA. .044 I.D. / 5 1/2 IN. / 0189037intravenous, cannula, fluid therapy, william o'shaughnessy, thomas latta

Trove : Advertised from 1937-1949 in various publications search under "Wellcome"' Calcium Borogluconate (yes with 2 'l's) . Victorian Government Gazette , no.2 Jan 5, 1960, page 16. List of Registered Stock Medicine. Registered Wholesale Dealer : Burroughs Wellcome and Co. (Aust) Ltd. Cressy Street, Rosebery New South Wales. Manufacturer, if other than the Wholesale Dealer - , Distinguishing Name of Stock Medicine : "Wellcome" Calcium Borogluconate, Approved Use or for the Treatment of : Milk Fever, hypocalcaemia. Rectangular faded pink cardboard box opening at both ends with the remnants of a paper label on one side, containing a folded paper leaflet and a cellophane bag containing white granules.Outer label '.....ATE .s enclosed)..........ELLCOME & .............STRALIA..D., SYDNEY, N....in Australia'. Impressed on one flap of box '132'. Printed leaflet (side one) Illustration of a unicorn, a thick black line under which text 'WELLCOME' brand CALCIUM BOROGLUCONATE (Vetinary)' followed by another thick black line. 'Calcium Borogluconate ia a stable , non-irritant calcium preparation for subcutaneous or intravenous injection in the treatment of milk fever and other forms of acute hypocalcaemia. It is available in the dry state as 'Wellcome' Calcium Borogluconate, a granular product in single dose containers of 2 1/2 oz. Milk Fever In the treatment of milk fever in cows, 21/2 oz. to 31/2 oz. of the granules should be injected subcutaneously at two or three points in the neck, with the usual aseptic precautions. The granules should be dissolved in 10 fl. oz. of boiling water, the solution allowed to boil for five minutes, then cooled to body temperature before administration. Repetition of the dose is very rarely necessary. Should a more rapid response be desired, the whole of the solution hay be given by slow intravenous injection; alternatively , the greater part of the solution may be injected by this route and the remainder given subcutaneously in the manner described above. A convenient apparatus for the controlled administration of large volumes of fluid (leaflet side two) is the 'Wellcome' Flutter Valve Injection Apparatus. Prophylaxis Recurrent attacks at successive parturitions may be prevented by giving calcium borogluconate immediately after calving and again about 20 hours later. Each dose should be from one or two ounces of 'Wellcome' Calcium Borogluconate, dissolved as directed above. Other Indications Certain other conditions have been found to respond readily to calcium borogluconate therapy. These include parturient hypocalcaemia or milk fever in ewes, parturient eclampsia in sows and bitches, so-called "staggers" in lactating dairy cattle suspected to be due to hypocalcaemia, and transit tetany in horses. The dosage for various species is generally within the ranges indicated below : horses and cattle 11/2 to 31/2 oz. Sheep, goats and pigs 1/2 oz. to 1 oz. Dogs 11/2 dr. to 3 dr. 'WELLCOME' brand CALCIUM BOROGLUCONATE A readily-soluble granular product issued in cartons of 21/2 oz.' Illustration of a unicorn, 'BURROUGHS WELLCOME & CO. (AUSTRALIA) LTD. (Incorporated in England) SYDNEY, N.S.W.' A black line 'ref.A5007g 54.1. 25' milk fever, hypocalcaemia, subcutaneous