Ethyl chloride was first used as a general anaesthetic in 1847, by Johann Ferdinand Heyfelder (1798-1869), a German surgeon. Once ethyl chloride became readily available, it was again taken up as a general anaesthetic in the late 1890s (USA). Ethyl chloride evaporates very quickly so that when it is sprayed onto the skin it produces very cold temperatures. “Refrigeration anesthesia”, or cryoanesthesia, refers to the anesthesia produced when the skin is significantly cooled.Due to its rapid onset, ethyl chloride was often used to induce general anaesthesia. It would be followed by a second anaesthetic, such as ether or nitrous oxide, which would be used for the remainder of the procedure. (The Wood Library Museum, 2016) The bottle has clear side and base mould seams which indicate it was made using a cup bottom mould.Glass bottle with paper label, metal fastening at the top and cream coloured plastic sealant at the neck. The bottle has clear side and base mould seams which indicate it was made using a cup bottom mould.Printed on main label at front: 100 c.c. 3 1/2 fl. ozs. / MEDICINAL CHEMICALS CORP [illegible] / MEDCO / ETHYL CHLORIDE / PURE / This Product conforms to all the re-/quirements of the BRITISH PHARMA-/COPCEIA, 1932, for / GENERAL ANAESTHESIA / Manufactured by / MEDICINAL CHEMICALS CORPORATION PTY. LIMITED / 39 Martin Place, Sydney Printed on round label on reverse side: 6d. / Cred [illegible]this container if returned in good order and condition. Stamped into underside of bottle: CM / S99ethyl chloride, medco, medicinal chemicals corporation pty. ltd, dr [e.s] holloway, bottle

The ethyl chloride was packaged in a glass bottle with increments measuring volume in milliletres printed on the galss surface in black. The bottle is sealed with a with metallic spray nozzle secured by a cork and moulded red plastic.The original cardboard packaging has red print on white background. The text reads 'Woolwich Elliott 100ml. Ethyl chloride B.P. for General anaesthesia - Woolwich-Eliott Chemical Company Pty. Ltd. Sydney Made in Australia.''BORONIA' stamped on the packaging in blue ink. It is located below the packaging text. ethyl chloride, chemical, woolwich-eliott, anaesthesia, general anaesthesia, glass

The glass phial contained liquid ethyl chloride, little pressure being required to liquefy the gas at room temperature. By directing the nozzle downwards at the skin or mucous membrane to be analgesed, a stream of liquid squirts out, vaporising on contact, thus producing transient local temperatures of approximately -10 qc. Ether's unpleasant smell agitated patients. Ethyl chloride's pleasant odour reduced agitation. It could be used for induction and worked quickly without irritating respiratory passages. Ethyl chloride spray could also be used as a local anaesthetic. Faded rectangular burgundy box containing a glass phial with metal and rubber lid that forms a spray nozzle. The lid of the box had a mustard coloured manufacturer's label wtih burgundy writing. The phial has a discoloured white label with red writing and a blue label with white writing.Printed in white ink on blue label: IMPORTANT / NOT DESTROY THIS TUBE, IT CAN / BE REFILLED FOR / 2/10bengue & co. ltd., london, ethyl chloride, 1900, local anaesthesia

The item was collected by Dr Geoffrey Kaye from a Vichy French military hospital during World war II.The inhaler comprises a black rubber face mask that connects to a metal circular chamber from which two white rubber valves are used to administer the anaesthetic agent. The ethyl chloride vials are labelled 'Kelene', a brand name. A waxed paper rebreather bag is attached to this metal chamer. mask, gas, anaesthesia, rebreather bag, world war ii, dr geoffrey kaye, ethyl chloride, kelene, french, vichy

Chloroethane, commonly known by its old name ethyl chloride, is a chemical compound with chemical formula CH3CH2Cl, once widely used in producing tetraethyllead, a gasoline additive. It is a colorless, flammable gas or refrigerated liquid with a faintly sweet odor. Originally, it was proposed as a general anaesthetic, filling the gap between the weaker narcotic nitrous oxide and the more powerful drugs ether and chloroform. 8670.1 - Dark blue cardboard lid. 8670.2 - Dark Blue cardboard box. 8670.3 - Cotton ball padding. 8670.4 - Semi circle cardboard. 8670.5 - Small rectangular boxes (2) placed either side of the top of the cylinder. 8670.6 - Glass cylinder with metal fitting. 8670.7 - Paper label on cylinder.- 100 c.c./- MEDCO./- 3 1/2 fl. oz./- ETHYL CHLORIDE./- Pure./- This conforms to all the requirements of the BRITISH PHARMACOPOEIA. 1932./- LOCAL ANAESTHESIA/- MEDICINAL CHEMICALS CORPOATION LIMITED. SYDNEY.

The glass phial contained liquid ethyl chloride. By directing the nozzle downwards at the skin a stream of liquid squirts out, vaporising on contact.. Ether's unpleasant smell agitated patients. Ethyl chloride's pleasant odour reduced agitation. It was used for controlling pain associated with injections and in minor surgical procedures. This item was used at Orbost Hospital.This item reflects the changes and development in medicine over the last century.A blue cardboard box containing a glass phial with metal lid that forms a spray nozzle. The lid of the box has a white manufacturer's label with blue writing. The phial has a discoloured white label with red writing.Ethyl chloride (pure) 100cc Woolwich for local anaestheticethyl-chloride chemical woolwich-eliott anaesthesia medical health orbost-hospital

Kelene is the proprietary name used for ethyl chloride in France which became synonymous with the agent in Europe. The manufacturer, Gilliard P. Monnet and Cartier of Lyon, also supplied Redard with his ampoules in 1890. Ethyl chloride was discovered by the French chemist Guillaume-Francois Rouelle in 1759; however it was not until 1901 that Frederic-Henri Basse manufactured sufficient for scientific study. Marie Jean-Pierre Flourens, Professor Comparative Anatomy at the University of Paris, first reported the effect of the inhalation of ethyl chloride after some experiments with and other agents in dogs. He described three experiments in which the dogs died, however death followed a period of insensibility as with ether although of much faster onset.Ten large glass phials containing 3g Kelene (Ethyl Chloride) stored in their original packaging. The box originally had twelve phials with now only ten remaining. Of the ten, 8 still contain the Kelene, 1 phial is empty but intact and 1 phial is broken. The cardboard box has a maroon paper cover, removable top with the product label and literature pasted across the base and top of the package. All product information is in French.ethyl chloride, kelene, local anaesthetic, gilliard p. monnet and cartier, france

This anesthetic ampoule, once containing pure Ethyl Chloride, was used from the 1930s to sedate patients before an operation. It was made and distributed by Sydney company Woolwich-Elliott Chemical Company Pty Ltd. The company had a recycling program, as indicated by the lable offering "6d [6 pence] will be allowed on return to us in good order and condition". This ampoule was donated to Flagstaff Hill Maritime Village by the family of Doctor William Roy Angus, Surgeon and Oculist. It is part of the “W.R. Angus Collection” includes historical medical equipment, surgical instruments and material once belonging to Dr Edward Ryan and Dr Thomas Francis Ryan, (both of Nhill, Victoria) as well as Dr Angus’s own belongings. The Collection’s history spans the medical practices of the two Doctors Ryan, from 1885-1926 plus that of Dr Angus, up until 1969. ABOUT THE “W.R.ANGUS COLLECTION” Doctor William Roy Angus M.B., B.S., Adel., 1923, F.R.C.S. Edin.,1928 (also known as Dr Roy Angus) was born in Murrumbeena, Victoria in 1901 and lived until 1970. He qualified as a doctor in 1923 at University of Adelaide, was Resident Medical Officer at the Royal Adelaide Hospital in 1924 and for a period was house surgeon to Sir (then Mr.) Henry Simpson Newland. Dr Angus was briefly an Assistant to Dr Riddell of Kapunda, then commenced private practice at Curramulka, Yorke Peninsula, SA, where he was physician, surgeon and chemist. In 1926, he was appointed as new Medical Assistant to Dr Thomas Francis Ryan (T.F. Ryan, or Tom), in Nhill, Victoria, where his experiences included radiology and pharmacy. In 1927 he was Acting House Surgeon in Dr Tom Ryan’s absence. Dr Angus had become engaged to Gladys Forsyth and they decided he further his studies overseas in the UK in 1927. He studied at London University College Hospital and at Edinburgh Royal Infirmary and in 1928, was awarded FRCS (Fellow from the Royal College of Surgeons), Edinburgh. He worked his passage back to Australia as a Ship’s Surgeon on the on the Australian Commonwealth Line’s T.S.S. Largs Bay. Dr Angus married Gladys in 1929, in Ballarat. (They went on to have one son (Graham 1932, born in SA) and two daughters (Helen (died 12/07/1996) and Berenice (Berry), both born at Mira, Nhill ) According to Berry, her mother Gladys made a lot of their clothes. She was very talented and did some lovely embroidery including lingerie for her trousseau and beautifully handmade baby clothes. Dr Angus was a ‘flying doctor’ for the A.I.M. (Australian Inland Ministry) Aerial Medical Service in 1928 . Its first station was in the remote town of Oodnadatta, where Dr Angus was stationed. He was locum tenens there on North-South Railway at 21 Mile Camp. He took up this ‘flying doctor’ position in response to a call from Dr John Flynn; the organisation was later known as the Flying Doctor Service, then the Royal Flying Doctor Service. A lot of his work during this time involved dental surgery also. Between 1928-1932 he was surgeon at the Curramulka Hospital, Yorke Peninsula, South Australia. In 1933 Dr Angus returned to Nhill and purchased a share of the Nelson Street practice and Mira hospital (a 2 bed ward at the Nelson Street Practice) from Dr Les Middleton one of the Middleton Brothers, the current owners of what previously once Dr Tom Ryan’s practice. Dr Tom and his brother had worked as surgeons included eye surgery. Dr Tom Ryan performed many of his operations in the Mira private hospital on his premises. He had been House Surgeon at the Nhill Hospital 1902-1926. Dr Tom Ryan had one of the only two pieces of radiology equipment in Victoria during his practicing years – The Royal Melbourne Hospital had the other one. Over the years Dr Tom Ryan had gradually set up what was effectively a training school for country general-practitioner-surgeons. Each patient was carefully examined, including using the X-ray machine, and any surgery was discussed and planned with Dr Ryan’s assistants several days in advance. Dr Angus gained experience in using the X-ray machine there during his time as assistant to Dr Ryan. When Dr Angus bought into the Nelson Street premises in Nhill he was also appointed as the Nhill Hospital’s Honorary House Surgeon 1933-1938. His practitioner’s plate from his Nhill surgery is now mounted on the doorway to the Port Medical Office at Flagstaff Hill Maritime Village, Warrnambool. When Dr Angus took up practice in the Dr Edward and Dr Tom Ryan’s old premises he obtained their extensive collection of historical medical equipment and materials spanning 1884-1926. A large part of this collection is now on display at the Port Medical Office at Flagstaff Hill Maritime Village in Warrnambool. In 1939 Dr Angus and his family moved to Warrnambool where he purchased “Birchwood,” the 1852 home and medical practice of Dr John Hunter Henderson, at 214 Koroit Street. (This property was sold in1965 to the State Government and is now the site of the Warrnambool Police Station. and an ALDI sore is on the land that was once their tennis court). The Angus family was able to afford gardeners, cooks and maids; their home was a popular place for visiting dignitaries to stay whilst visiting Warrnambool. Dr Angus had his own silk worm farm at home in a Mulberry tree. His young daughter used his centrifuge for spinning the silk. Dr Angus was appointed on a part-time basis as Port Medical Officer (Health Officer) in Warrnambool and held this position until the 1940’s when the government no longer required the service of a Port Medical Officer in Warrnambool; he was thus Warrnambool’s last serving Port Medical Officer. (Masters of immigrant ships arriving in port reported incidents of diseases, illness and death and the Port Medical Officer made a decision on whether the ship required Quarantine and for how long, in this way preventing contagious illness from spreading from new immigrants to the residents already in the colony.) Dr Angus was a member of the Australian Medical Association, for 35 years and surgeon at the Warrnambool Base Hospital 1939-1942, He served with the Australian Department of Defence as a Surgeon Captain during WWII 1942-45, in Ballarat, Victoria, and in Bonegilla, N.S.W., completing his service just before the end of the war due to suffering from a heart attack. During his convalescence he carved an intricate and ‘most artistic’ chess set from the material that dentures were made from. He then studied ophthalmology at the Royal Melbourne Eye and Ear Hospital and created cosmetically superior artificial eyes by pioneering using the intrascleral cartilage. Angus received accolades from the Ophthalmological Society of Australasia for this work. He returned to Warrnambool to commence practice as an ophthalmologist, pioneering in artificial eye improvements. He was Honorary Consultant Ophthalmologist to Warrnambool Base Hospital for 31 years. He made monthly visits to Portland as a visiting surgeon, to perform eye surgery. He represented the Victorian South-West subdivision of the Australian Medical Association as its secretary between 1949 and 1956 and as chairman from 1956 to 1958. In 1968 Dr Angus was elected member of Spain’s Barraquer Institute of Barcelona after his research work in Intrasclearal cartilage grafting, becoming one of the few Australian ophthalmologists to receive this honour, and in the following year presented his final paper on Living Intrasclearal Cartilage Implants at the Inaugural Meeting of the Australian College of Ophthalmologists in Melbourne In his personal life Dr Angus was a Presbyterian and treated Sunday as a Sabbath, a day of rest. He would visit 3 or 4 country patients on a Sunday, taking his children along ‘for the ride’ and to visit with him. Sunday evenings he would play the pianola and sing Scottish songs to his family. One of Dr Angus’ patients was Margaret MacKenzie, author of a book on local shipwrecks that she’d seen as an eye witness from the late 1880’s in Peterborough, Victoria. In the early 1950’s Dr Angus, painted a picture of a shipwreck for the cover jacket of Margaret’s book, Shipwrecks and More Shipwrecks. She was blind in later life and her daughter wrote the actual book for her. Dr Angus and his wife Gladys were very involved in Warrnambool’s society with a strong interest in civic affairs. He had an interest in people and the community They were both involved in the creation of Flagstaff Hill, including the layout of the gardens. After his death (28th March 1970) his family requested his practitioner’s plate, medical instruments and some personal belongings be displayed in the Port Medical Office surgery at Flagstaff Hill Maritime Village, and be called the “W. R. Angus Collection”. The anesthetic ampoule, once containing pure Ethyl Chloride, is an example of the medication used in surgery in the early to mid 1900's. The W.R. Angus Collection is significant for still being located at the site it is connected with, Doctor Angus being the last Port Medical Officer in Warrnambool. The collection of medical instruments and other equipment is culturally significant, being an historical example of medicine from late 19th to mid-20th century. Dr Angus assisted Dr Tom Ryan, a pioneer in the use of X-rays and in ocular surgery. Medication ampoule once containing Ethyl Chloride, a pure local anesthetic. Glass cylinder with metal closure, once used in the 1930s, VERY FRAGILE. Part of the W.R. Angus Collection. Contained 100cc; made in Australia by Woolwich-Elliott Chemical Company Pty Ltd, of Sydney. Printed text on label includes "ELLIOTT'S ETHYL CHLORIDE (PURE) 100cc / FOR LOCAL ANAESTHESIA / Manufactured by Woolwich-Elliott Chemical Company Pty Ltd, Sydney / Made in Australia" and "Conforming with requirements of the British Pharmacopeia 1932". Another label is printed "6d will be allowed on return to us in good order and condition"flagstaff hill, warrnambool, shipwrecked coast, flagstaff hill maritime museum, maritime museum, shipwreck coast, flagstaff hill maritime village, great ocean road, dr w r angus, dr ryan, surgical instrument, t.s.s. largs bay, warrnambool base hospital, nhill base hospital, mira hospital, flying doctor, surgical preparation, surgical medication, medicaiton ampoule, anesthetic ampoule, pure ethyl chloride, woolwich-elliott chemical company pty ltd,

The glass phial contained liquid ethyl chloride. By directing the nozzle downwards at the skin a stream of liquid squirts out, vaporising on contact.. Ether's unpleasant smell agitated patients. Ethyl chloride's pleasant odour reduced agitation. It was used for controlling pain associated with injections and in minor surgical procedures. This item was used at Orbost Hospital. This item reflects the changes and development in medicine over the last century.A blue cardboard box containing a glass phial with metal lid that forms a spray nozzle. The phial has a discoloured white label with red writing.ethyl-chloride chemical woolwich-eliott anaesthesia medical health orbost-hospital

This photo album depicts a small period of time during 1919, and highlights some of the anaesthetic work conducted by Dr Rupert Hornabrook. There is no record as to the reason for the construction of the album, but it appears to offer insight into his work the Dental School, as well as experimentation with different types of anaesthetic agents, using himself as a test subject.Rupert Hornabrook was an early full-time anaesthetist in Australia. He helped to develop anaesthesia into a specialised field of medicine by conducting research into the way anaesthesia worked, and its effects on the body. This album is of historic significance as it not only documents a specific period in the professional life of a full-time anaesthetist in Australia, it also documents anaesthetic equipment, and the way it was used.Blue photograph album with vinyl wrapped heavy card cover. A three ringed binder is attached to the inside of the album and sixteen (16) photographs are inside, mounted on heavy card. Each photograph has a typed label on white paper in blue ink adhered to the front describing the events of the photograph. Photographs depict various administrations of ethyl chloride as anaesthesia and analgesia, with many photographs of Rupert Hornabrook.

Dr Thomas Small designed this ether anaesthesia and analgesia machine while he was an Honorary Medical Officer at the Royal Women's Hospital in Sydney during the 1930s. The inhaler is compact and portable. Initially, Small experimented with other agents for the relief of labour pain but was not happy with any of them. He also tried various agents on himself, including nitrous oxide/oxygen, chloroform and ethyl chloride. Finally he settled on ether via a Clover inhaler as the best analgesic. This inhaler is only described in use in Australia and New Zealand, although it was used for almost 40 years. Black leather box with leather handle, lockable latches on either side and drop down front case panel containing a metal ether inhaler and length of black corrugated rubber hose with one end attached to the inhaler and the other end open for attaching a mask. The metal inhaler drum is circular and attached to the floor of the case with a small tap/lever to one side and a mixing valve on the top near the hose connection. The lever has incised gradings of quarter increments from 0 to 1. The box is designed for the ether inhaler to be portable.ether, small, thomas, analgesia, obstetrics, anaesthesia, anaesthetic, royal women's, sydney, queen victoria, melbourne